Authors
Keyur D. Bhatt, Kavit S. Mehta, Bharat A. Makwana, Surbhi V. Upadhyay
Abstract
The molecular sensors growth for well-organized detection of detailed metal ion is a developing part in chemistry for the reason of their applications of potential analytical in various diverse grounds, comprising biology with chemistry, for determination of selectivity with various metal ions, method of fluorescent has been extensively used. Fluorescent molecular metal ion sensors turn into progressively essential as device for the measureable real-time observing of metal ion application in biological models. In these measuring device, a metal chelating site is regularly connected to fluorophore, and metal requisite affects the intensity of fluorescence of the compound. Keywords: Fluorescence sensor, Calix system, Metal ions, Macrocyclic compounds
Introduction
Macrocyclic chemistry is different from the other because it deals with synthetic molecular systems that are held together by weaker non-covalent interactions, such as electrostatic forces, hydrogen bonds, π-π stacking interactions, van der Waals forces, or hydrophobic effects1-3. Toxic metals are extensively used in industrial, agricultural and military purposes for several decades of time. These are now widely dispersed in a range of different forms, and there are environmental problems arising from their mining, extraction and purification4-6. Not only cations, the anions, specially halides and oxo anions play a fundamental role for resolving various chemical, biological and environmental issues Toxic heavy metal ions such as Hg2+, Pb2+ and Cd2+, which are highly health hazardous, require detection of their presence in the environment in ppm level7. Specially lead interferes with a variety of body processes and is toxic to many organs and tissues including the heart, bones, intestines, kidneys, reproductive and nervous systems8. It interferes with the development of the nervous system and is therefore particularly toxic to children, causing potentially permanent learning and behavior disorders. Mercury has a number of effects on humans like disruption of the nervous system, damage to brain functions, DNA damage and chromosomal damage. Since anions are ubiquitous and play important roles in many biological and chemical systems, there is an increasing interest in the design and development of receptors that selectively recognize specific anions such as halides, NO3-, SO42-, PO43-, H2PO4-. Among the range of biologically important anions, the fluoride anion has attracted growing attention due to its established role in preventing dental cares. Fluoride anion is also explored extensively as a treatment for osteoporosis, a type of fluoride toxicity that generally manifests itself clinically in terms of increasing bone density. Acetate is a critical component of numerous metabolic processes9, 10. Acetate production and oxidation rate have been frequently used as indicator of organic decomposition in marine sediments. Phosphate anions are very important anionic species in living organisms.
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| APA Style | Bhatt et al (2019). A Mini Review on: Fluorescent Sensors for Toxic Metal ions. Academic Journal of Material Sciences, 1(1), 1-5 |
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